LymphedemaV1, Main, Exploration, bibRecord, 00DC26

Indium-111 labelled granulocyte scanning to detect inflammation in the lungs of patients with chronic sputum expectoration.

Identifieur interne : 00DC26 ( Main/Exploration ); précédent : 00DC25; suivant : 00DC27

Indium-111 labelled granulocyte scanning to detect inflammation in the lungs of patients with chronic sputum expectoration.

Auteurs : D C Currie [Royaume-Uni] ; A M Peters [Royaume-Uni] ; N D Garbett [Royaume-Uni] ; P. George [Royaume-Uni] ; B. Strickland [Royaume-Uni] ; J P Lavender [Royaume-Uni] ; P J Cole [Royaume-Uni]

Source :

Thorax [ 0040-6376 ] ; 1990-07.

RBID : ISTEX:4DDDBADCF000FCCF11EEAA71ADDA00235E042949

Abstract

Thirty eight patients with chronic sputum expectoration underwent indium-111 labelled granulocyte lung scanning and measurement of whole body loss of indium-111 labelled granulocytes. Twenty four patients had radiologically proved bronchiectasis and 14 had mucus hypersecretion without radiological evidence of bronchiectasis. None was having an acute exacerbation at the time of the scan. The median 24 hour volume of sputum expectorated was 17 (range 2-175) ml. The 24 hour volume of purulent sputum was 5 (0-142) ml; six patients expectorated mucoid sputum only. Twenty one of the 38 patients had a positive granulocyte lung scan. All nine patients expectorating more than 20 ml purulent sputum in 24 hours had positive lung scans and all had lost more than 19% of the indium-111 from the body after five to seven days. Of the six patients with mucoid sputum, only one had a positive scan and these subjects lost only 6-11% of the indium-111 in five to seven days. The percentage loss of indium-111 from the body correlated with 24 hour purulent sputum volume (r = 0.41, n = 38, p less than 0.001) and total elastolytic activity in 24 hour sputum (r = 0.54, n = 14, p less than 0.01). The loss of indium-111 was not related to the extent of bronchiectasis when purulent sputum volume was allowed for. Indium-111 labelled granulocyte scanning provides a sensitive and objective method for detecting inflammation in the lungs and should help to improve understanding of chronic bronchial sepsis and possibly treatment in selected cases.

Url:

DOI: 10.1136/thx.45.7.541

Affiliations:

Le document en format XML

<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Indium-111 labelled granulocyte scanning to detect inflammation in the lungs of patients with chronic sputum expectoration.</title>
<author><name sortKey="Currie, D C" sort="Currie, D C" uniqKey="Currie D" first="D C" last="Currie">D C Currie</name>
</author>
<author><name sortKey="Peters, A M" sort="Peters, A M" uniqKey="Peters A" first="A M" last="Peters">A M Peters</name>
</author>
<author><name sortKey="Garbett, N D" sort="Garbett, N D" uniqKey="Garbett N" first="N D" last="Garbett">N D Garbett</name>
</author>
<author><name sortKey="George, P" sort="George, P" uniqKey="George P" first="P" last="George">P. George</name>
</author>
<author><name sortKey="Strickland, B" sort="Strickland, B" uniqKey="Strickland B" first="B" last="Strickland">B. Strickland</name>
</author>
<author><name sortKey="Lavender, J P" sort="Lavender, J P" uniqKey="Lavender J" first="J P" last="Lavender">J P Lavender</name>
</author>
<author><name sortKey="Cole, P J" sort="Cole, P J" uniqKey="Cole P" first="P J" last="Cole">P J Cole</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:4DDDBADCF000FCCF11EEAA71ADDA00235E042949</idno>
<date when="1990" year="1990">1990</date>
<idno type="doi">10.1136/thx.45.7.541</idno>
<idno type="url">https://api.istex.fr/document/4DDDBADCF000FCCF11EEAA71ADDA00235E042949/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">002382</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">002382</idno>
<idno type="wicri:Area/Istex/Curation">002382</idno>
<idno type="wicri:Area/Istex/Checkpoint">005586</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">005586</idno>
<idno type="wicri:doubleKey">0040-6376:1990:Currie D:indium:labelled:granulocyte</idno>
<idno type="wicri:Area/Main/Merge">00E836</idno>
<idno type="wicri:source">PMC</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC462585</idno>
<idno type="RBID">PMC:462585</idno>
<idno type="wicri:Area/Pmc/Corpus">001A56</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001A56</idno>
<idno type="wicri:Area/Pmc/Curation">001A55</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001A55</idno>
<idno type="wicri:Area/Pmc/Checkpoint">004396</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">004396</idno>
<idno type="wicri:Area/Ncbi/Merge">005C52</idno>
<idno type="wicri:Area/Ncbi/Curation">005C52</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">005C52</idno>
<idno type="wicri:doubleKey">0040-6376:1990:Currie D:indium:labelled:granulocyte</idno>
<idno type="wicri:Area/Main/Merge">00E608</idno>
<idno type="wicri:Area/Main/Curation">00DC26</idno>
<idno type="wicri:Area/Main/Exploration">00DC26</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Indium-111 labelled granulocyte scanning to detect inflammation in the lungs of patients with chronic sputum expectoration.</title>
<author><name sortKey="Currie, D C" sort="Currie, D C" uniqKey="Currie D" first="D C" last="Currie">D C Currie</name>
<affiliation wicri:level="3"><country>Royaume-Uni</country>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
<wicri:orgArea>Department of Thoracic Medicine, National Heart and Lung Institute</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Peters, A M" sort="Peters, A M" uniqKey="Peters A" first="A M" last="Peters">A M Peters</name>
<affiliation wicri:level="3"><country>Royaume-Uni</country>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
<wicri:orgArea>Department of Thoracic Medicine, National Heart and Lung Institute</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Garbett, N D" sort="Garbett, N D" uniqKey="Garbett N" first="N D" last="Garbett">N D Garbett</name>
<affiliation wicri:level="3"><country>Royaume-Uni</country>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
<wicri:orgArea>Department of Thoracic Medicine, National Heart and Lung Institute</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="George, P" sort="George, P" uniqKey="George P" first="P" last="George">P. George</name>
<affiliation wicri:level="3"><country>Royaume-Uni</country>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
<wicri:orgArea>Department of Thoracic Medicine, National Heart and Lung Institute</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Strickland, B" sort="Strickland, B" uniqKey="Strickland B" first="B" last="Strickland">B. Strickland</name>
<affiliation wicri:level="3"><country>Royaume-Uni</country>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
<wicri:orgArea>Department of Thoracic Medicine, National Heart and Lung Institute</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Lavender, J P" sort="Lavender, J P" uniqKey="Lavender J" first="J P" last="Lavender">J P Lavender</name>
<affiliation wicri:level="3"><country>Royaume-Uni</country>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
<wicri:orgArea>Department of Thoracic Medicine, National Heart and Lung Institute</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Cole, P J" sort="Cole, P J" uniqKey="Cole P" first="P J" last="Cole">P J Cole</name>
<affiliation wicri:level="3"><country>Royaume-Uni</country>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
<wicri:orgArea>Department of Thoracic Medicine, National Heart and Lung Institute</wicri:orgArea>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Thorax</title>
<title level="j" type="abbrev">Thorax</title>
<idno type="ISSN">0040-6376</idno>
<idno type="eISSN">1468-3296</idno>
<imprint><publisher>BMJ Publishing Group Ltd and British Thoracic Society</publisher>
<date type="published" when="1990-07">1990-07</date>
<biblScope unit="volume">45</biblScope>
<biblScope unit="issue">7</biblScope>
<biblScope unit="page" from="541">541</biblScope>
</imprint>
<idno type="ISSN">0040-6376</idno>
</series>
<idno type="istex">4DDDBADCF000FCCF11EEAA71ADDA00235E042949</idno>
<idno type="DOI">10.1136/thx.45.7.541</idno>
<idno type="href">thoraxjnl-45-541.pdf</idno>
<idno type="PMID">2396234</idno>
<idno type="local">thoraxjnl;45/7/541</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0040-6376</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass></textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Thirty eight patients with chronic sputum expectoration underwent indium-111 labelled granulocyte lung scanning and measurement of whole body loss of indium-111 labelled granulocytes. Twenty four patients had radiologically proved bronchiectasis and 14 had mucus hypersecretion without radiological evidence of bronchiectasis. None was having an acute exacerbation at the time of the scan. The median 24 hour volume of sputum expectorated was 17 (range 2-175) ml. The 24 hour volume of purulent sputum was 5 (0-142) ml; six patients expectorated mucoid sputum only. Twenty one of the 38 patients had a positive granulocyte lung scan. All nine patients expectorating more than 20 ml purulent sputum in 24 hours had positive lung scans and all had lost more than 19% of the indium-111 from the body after five to seven days. Of the six patients with mucoid sputum, only one had a positive scan and these subjects lost only 6-11% of the indium-111 in five to seven days. The percentage loss of indium-111 from the body correlated with 24 hour purulent sputum volume (r = 0.41, n = 38, p less than 0.001) and total elastolytic activity in 24 hour sputum (r = 0.54, n = 14, p less than 0.01). The loss of indium-111 was not related to the extent of bronchiectasis when purulent sputum volume was allowed for. Indium-111 labelled granulocyte scanning provides a sensitive and objective method for detecting inflammation in the lungs and should help to improve understanding of chronic bronchial sepsis and possibly treatment in selected cases.</div>
</front>
</TEI>
<affiliations><list><country><li>Royaume-Uni</li>
</country>
<region><li>Angleterre</li>
<li>Grand Londres</li>
</region>
<settlement><li>Londres</li>
</settlement>
</list>
<tree><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Currie, D C" sort="Currie, D C" uniqKey="Currie D" first="D C" last="Currie">D C Currie</name>
</region>
<name sortKey="Cole, P J" sort="Cole, P J" uniqKey="Cole P" first="P J" last="Cole">P J Cole</name>
<name sortKey="Garbett, N D" sort="Garbett, N D" uniqKey="Garbett N" first="N D" last="Garbett">N D Garbett</name>
<name sortKey="George, P" sort="George, P" uniqKey="George P" first="P" last="George">P. George</name>
<name sortKey="Lavender, J P" sort="Lavender, J P" uniqKey="Lavender J" first="J P" last="Lavender">J P Lavender</name>
<name sortKey="Peters, A M" sort="Peters, A M" uniqKey="Peters A" first="A M" last="Peters">A M Peters</name>
<name sortKey="Strickland, B" sort="Strickland, B" uniqKey="Strickland B" first="B" last="Strickland">B. Strickland</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 00DC26 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 00DC26 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Sante
   |area=    LymphedemaV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     ISTEX:4DDDBADCF000FCCF11EEAA71ADDA00235E042949
   |texte=   Indium-111 labelled granulocyte scanning to detect inflammation in the lungs of patients with chronic sputum expectoration.
}}

This area was generated with Dilib version V0.6.31.
Data generation: Sat Nov 4 17:40:35 2017. Site generation: Tue Feb 13 16:42:16 2024

Serveur d'exploration sur le lymphœdème

Indium-111 labelled granulocyte scanning to detect inflammation in the lungs of patients with chronic sputum expectoration.

Indium-111 labelled granulocyte scanning to detect inflammation in the lungs of patients with chronic sputum expectoration.

Source :

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	Serveur d'exploration sur le lymphœdème
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.